G R Scott Budinger Selected Research

Inflammasomes

1/2021	miR-221-5p-Mediated Downregulation of JNK2 Aggravates Acute Lung Injury.
1/2018	Inflammatory Monocytes Drive Influenza A Virus-Mediated Lung Injury in Juvenile Mice.
3/2015	Vimentin regulates activation of the NLRP3 inflammasome.

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.

Realize the full power of the drug-disease research graph!

G R Scott Budinger Research Topics

Disease

19	Lung Injury 07/2023 - 01/2005
19	Fibrosis (Cirrhosis) 06/2021 - 10/2005
18	Pulmonary Fibrosis (Fibrosing Alveolitis) 01/2022 - 03/2006
17	Pneumonia (Pneumonitis) 03/2024 - 03/2006
15	Hypoxia (Hypoxemia) 01/2018 - 04/2002
13	Respiratory Distress Syndrome (Acute Respiratory Distress Syndrome) 04/2022 - 01/2005
12	Infections 05/2024 - 01/2012
12	COVID-19 03/2024 - 01/2020
9	Hypercapnia 01/2024 - 01/2012
8	Inflammation (Inflammations) 01/2023 - 06/2011
7	Primary Graft Dysfunction 07/2023 - 10/2016
7	Lung Diseases (Lung Disease) 01/2023 - 01/2016
7	Human Influenza (Influenza) 01/2020 - 01/2012
7	Acute Lung Injury 03/2015 - 01/2005
7	Hyperoxia 01/2012 - 05/2002
6	Thrombosis (Thrombus) 10/2021 - 10/2007
5	Idiopathic Pulmonary Fibrosis 01/2022 - 09/2011
4	Respiratory Insufficiency (Respiratory Failure) 03/2024 - 12/2020
4	Asthma (Bronchial Asthma) 01/2022 - 01/2015
4	Neoplasms (Cancer) 01/2020 - 05/2010
3	Critical Illness (Critically Ill) 01/2022 - 04/2013
3	Chronic Obstructive Pulmonary Disease (COPD) 01/2020 - 01/2010
2	Reperfusion Injury 10/2022 - 01/2018
2	Interstitial Lung Diseases (Interstitial Lung Disease) 01/2022 - 01/2020
2	Ventilator-Associated Pneumonia 12/2020 - 09/2005
2	Splenomegaly 12/2017 - 10/2015
2	Lymphadenopathy 12/2017 - 10/2015
2	Systemic Scleroderma (Systemic Sclerosis) 01/2016 - 11/2011
2	Respiratory Hypersensitivity 01/2016 - 02/2015
2	Disease Progression 04/2015 - 07/2014
2	Lung Neoplasms (Lung Cancer) 01/2012 - 05/2010
1	Cognitive Dysfunction 03/2024
1	Dementia (Dementias) 03/2024
1	Chronic Renal Insufficiency 07/2023

Drug/Important Bio-Agent (IBA)

18	Proteins (Proteins, Gene)FDA Link 12/2023 - 04/2002
14	Bleomycin (Blenoxane)FDA LinkGeneric 01/2022 - 10/2005
11	Mitochondrial DNA (mtDNA)IBA 06/2021 - 04/2002
8	AsbestosIBA 06/2021 - 01/2015
8	Reactive Oxygen Species (Oxygen Radicals)IBA 12/2017 - 05/2002
7	Particulate MatterIBA 10/2021 - 06/2006
7	Adenosine Triphosphatases (ATPase)IBA 11/2017 - 05/2006
6	CytokinesIBA 03/2024 - 10/2007
6	RNA (Ribonucleic Acid)IBA 03/2024 - 01/2019
6	Prostaglandins DIBA 07/2023 - 10/2016
6	CateninsIBA 01/2023 - 11/2011
6	Interleukin-6 (Interleukin 6)IBA 01/2019 - 04/2005
6	AntioxidantsIBA 12/2017 - 05/2002
4	UbiquitinIBA 01/2021 - 05/2006
4	Messenger RNA (mRNA)IBA 01/2021 - 09/2011
4	Transforming Growth Factors (Transforming Growth Factor)IBA 04/2015 - 02/2012
4	Oxygen (Dioxygen)IBA 04/2013 - 02/2004
4	Adenosine Triphosphate (ATP)IBA 05/2010 - 01/2007
4	Cytochromes c (Cytochrome c)IBA 02/2004 - 04/2002
3	Antiviral Agents (Antivirals)IBA 01/2024 - 01/2020
3	Anti-Bacterial Agents (Antibiotics)IBA 10/2021 - 10/2015
3	InflammasomesIBA 01/2021 - 03/2015
3	Electron Transport Complex III (Coenzyme Q-Cytochrome-c Reductase)IBA 01/2020 - 06/2007
3	Small Interfering RNA (siRNA)IBA 01/2018 - 05/2006
3	CollagenIBA 01/2017 - 09/2011
3	Transcription Factors (Transcription Factor)IBA 05/2013 - 04/2002
3	Transforming Growth Factor beta1 (TGF beta 1)IBA 02/2010 - 01/2005
3	Superoxide DismutaseIBA 07/2006 - 02/2004
3	Caspase 9IBA 05/2002 - 04/2002
2	Interferon Type IIBA 04/2024 - 12/2017
2	Ubiquitin-Protein Ligases (Ubiquitin-Protein Ligase)IBA 04/2024 - 01/2019
2	ChemokinesIBA 03/2024 - 01/2020
2	Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA 01/2023 - 01/2012
2	LipopolysaccharidesIBA 01/2023 - 05/2013
2	SmokeIBA 01/2023 - 01/2020
2	AutoantibodiesIBA 10/2022 - 12/2017
2	Immunoglobulin G (IgG)IBA 10/2022 - 12/2017
2	Caspase 3 (Caspase-3)IBA 10/2021 - 01/2015
2	Sirtuin 3IBA 06/2021 - 01/2017
2	Crocidolite Asbestos (Blue Asbestos)IBA 06/2021 - 01/2015
2	Protein Kinases (Protein Kinase)IBA 01/2021 - 01/2018
2	Metformin (Glucophage)FDA LinkGeneric 02/2019 - 01/2019
2	protein kinase C zetaIBA 11/2017 - 09/2014
2	Methacholine Chloride (Methacholine)FDA Link 01/2016 - 02/2015
2	Toll-Like Receptors (Toll-Like Receptor)IBA 01/2016 - 01/2013
2	CaspasesIBA 10/2015 - 02/2004
2	Laminin (Merosin)IBA 04/2015 - 09/2011
2	Nitric Oxide (Nitrogen Monoxide)FDA Link 01/2015 - 05/2002
2	LeptinIBA 01/2014 - 06/2011
2	Proteasome InhibitorsIBA 02/2012 - 05/2006
2	Oxidants (Oxidizing Agents)IBA 06/2011 - 04/2011
2	EUK-134IBA 05/2009 - 02/2004
2	Rieske iron-sulfur proteinIBA 06/2007 - 05/2006
2	CatalaseIBA 05/2006 - 02/2004
1	AlbuminsIBA 05/2024
1	Adrenal Cortex Hormones (Corticosteroids)IBA 03/2024
1	Nucleocapsid ProteinsIBA 12/2023
1	InterferonsIBA 12/2023
1	PolyproteinsIBA 12/2023
1	T-Cell Antigen Receptors (T-Cell Receptor)IBA 12/2023

Therapy/Procedure

15	Lung Transplantation 05/2024 - 01/2016
15	Therapeutics 01/2023 - 02/2010
7	Transplantation 05/2024 - 07/2014
4	Mechanical Ventilators (Ventilator) 01/2023 - 01/2016
4	Extracorporeal Membrane Oxygenation 04/2022 - 11/2018
3	Artificial Respiration (Mechanical Ventilation) 01/2022 - 11/2018